| Development of a CMOS Array for Toxicity Monitoring |
| Collaborators |
| Overview of Talk |
| Part I: Introduction and Background |
| Goal: Online Toxicity Testing |
| Role of DNA |
| Nucleic Acid Review |
| Project Logic |
| Does TCE affect gene expression in the heart? |
| Does TCE affect gene expression in the heart? |
| Improvements in Methodology |
| Slide 12 |
| Microarray Measurement of Differential Gene Expression |
| Power of Approach |
| Drawbacks of Conventional Technology |
| Part II: Current Project |
| Slide 17 |
| CMOS Microarray |
| State of the Art |
| Features of the Prototype Chip (a-version) |
| AutoCAD Illustration of New Prototype Chip (b-version) |
| Procedural Overview |
| Microarray on a Chip |
| DNA Microarray |
| DNA Microarray |
| DNA Microarray |
| Advantages |
| Potential Applications |
| Slide 29 |
| Experimental Set-up |
| Progress to Date |
| Research Ahead |
| Thank You |