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2014 - |
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Jan. 9, 2014 |
Host: Jane
Chang, Professor and Associate Dean, Chemical and Biomolecular Engineering,
University of California-Los Angeles
Presented by: Jane Chang, University of California, Los
Angeles
Topic title:
“Assessment of non-PFC
Chemistries for Etching Carbon-Doped Silica”
Abstract:
In
this work, a thermodynamic approach is used to assess the feasibility of
various etch chemistries for etching carbon doped silica for back end of
line (BEOL) applications, beginning with the consideration of reactions
between the dominant vapor phase/condensed species and the surface at
various temperatures and reactant partial pressures. The volatility of etch
product was determined to aid the selection of viable etch chemistry,
leading to viable etch rates with reduced environmental impact. The effect
of carbon doping in silica on the attainable etch efficacy was determined.
A number of alternative chemistries were investigated in carbon-doped silica
etch such as NF3 and CF3I. (PDF) |
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Feb. 6 |
CANCELLED |
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March 6 |
Host: Denis
Fourches and Alex Tropsha, University of North Carolina, Chapel Hill
resented by:
Dr. Rachael Crist, Scientist at the National Cancer Institute (NCI)’s
Nanotechnology Characterization Laboratory (NCL)
Topic title: “Preclinical
Characterization of Nanomedicines: Lessons Learned from NCI’s Nanotechnology
Characterization Lab (NCL)”
Abstract: The Nanotechnology
Characterization Laboratory (NCL) is a formal collaboration among the
National Cancer Institute (NCI), the U.S. Food and Drug Administration (FDA)
and the National Institute of Standards and Technology (NIST). Established
in 2004, the NCL conducts preclinical characterization of nanoparticles
intended as cancer therapeutics and diagnostics. The NCL uses a three-tiered
Assay Cascade to thoroughly characterize a nanoparticle’s physical and
chemical attributes, the in vitro immunological and toxicological
properties, and the in vivo efficacy and safety (ADME/Tox) profiles using
animal models. The NCL has validated more than 40 physicochemical and in
vitro protocols as part of this Assay Cascade, and made them freely
available at
http://ncl.cancer.gov. To
date, more than 300 different nanoparticles, including dendrimers, liposomes,
metals and metal oxides, polymers, and more, have gone through the NCL’s
Assay Cascade. The NCL is a free government resource, available via an
application process, to nanotech researchers from all backgrounds, including
academia, industry and government. This presentation will provide an
overview of the NCL and discuss some of the NCL’s “Lessons Learned”. Funded
by NCI Contract # HHSN261200800001E.
About the presenter: Dr. Rachael Crist is a Scientist at the
National Cancer Institute (NCI)’s Nanotechnology Characterization Laboratory
(NCL), a formal collaboration among NCI, the National Institute of Science
and Technology (NIST) and the Food and Drug Administration (FDA),
specializing in the preclinical characterization of cancer nanomedicines.
Since its inception in 2004, the NCL has assisted in the advancement of
seven nanotech cancer products into clinical trials, including those from
CytImmune Sciences, Nanospectra Biosciences, BIND Therapeutics, and Azaya
Therapeutics. At the NCL, Dr. Crist is part of a team of scientists
responsible for evaluating candidate nanotech drugs and diagnostics with
regards to physical and chemical attributes, in vitro biological profiles,
and in vivo safety and efficacy profiles. Dr. Crist is responsible for the
NCL’s scientific and technical writing, assists with the preclinical data
analysis, and helps coordinate the NCL's data management, project
management, and interactions with NCL’s collaborators. Her areas of
expertise include organic chemistry, molecular biology, and protein
chemistry. Dr. Crist has experience in a variety of issues related to
nanotech drug development and environmental, health and safety (EHS) issues.
She received her Ph.D. degree in bio-organic chemistry from Michigan State
University in 2004, and her B.S. degree in chemistry from Miami University
in 1998. (PDF) |
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April 3 |
POSTPONED: TBA
Host:
Farhang Shadman, Chemical and Environmental Engineering, University of
Arizona |
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May 1 |
Host:
Paul Pantano,
Associate Professor of Analytical Chemistry, The University of Texas at
Dallas
Presented by:
Elizabeth Braun, Ph.D.
Chemistry Candidate, The University of Texas at Dallas
Topic title: "The Importance of an Extensive Elemental
Analysis of Carbon Nanotube Soot"
Abstract: Few manufacturers provide elemental
analysis information on the certificates of analysis of their single-walled
carbon nanotube (SWCNT) soot products, and those who do primarily perform
surface sensitive analyses that may not accurately represent the bulk
properties of heterogeneous soot samples. Since the accurate elemental
analysis of SWCNT soot is a requisite for exacting assessments of product
quality and environmental health and safety (EH&S) risk, the purpose of this
work was to develop a routine laboratory procedure for an extensive
elemental analysis of SWCNT soot using bulk methods of analyses. Herein, a
combination of carbon, hydrogen, nitrogen, sulfur, and oxygen (CHNS/O)
combustion analyses, oxygen flask combustion/anion chromatography (OFC/AC),
graphite furnace-atomic absorption spectroscopy (GF-AAS), and inductively
coupled plasma-mass spectroscopy (ICP-MS) were used to generate a 77-element
analysis of two as-received CoMoCAT® SWCNT soot products. Twenty four
elements were detected in one product, thirty six in the other, and each
data set was compared to its respective certificate of analysis. The
addition of the OFC/AC results improved the accuracy of elements detected by
GF-AAS and ICP-MS, and an assessment was performed on the results that
concluded that the trace elemental impurities should not pose an EH&S
concern if these soot products became airborne. (PDF) |
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June 5 |
Host:
Shyam Aravamudhan,
Assistant Professor of Nanoengineering, Joint School of Nanoscience and
Nanoengineering, North Carolina A&T State University and The University of
North Carolina at Greensboro
Presented by:
Karshak Kosaraju, PhD
Student, Joint School of Nanoscience and Nanoengineering, North Carolina A&T
State University and The University of North Carolina at Greensboro
Topic title:
“Studying the cellular
uptake and toxicity of CMP Nanoparticles (NPs)”
Abstract:
With the increasing use
of engineered NPs for various applications, it is really important to
understand the cellular uptake mechanism along with toxicity. During the
annual review, we presented the results from the cellular toxicity
experiments with CMP slurries. During this presentation, we will emphasize
on some important findings in toxicity along with spectroscopic and
electrochemical methods to study the cellular uptake of NPs in slurries. In
an attempt to understand the cellular uptake of CMP NPs, we employed a
number of techniques including Confocal Raman, ICP-OES (Inductively Couples
Plasma-Optical Emissions and ECIS (Electrochemical Cell-substrate Impedance
Sensing). The results obtained from these techniques indicated indicate the
reliable cellular uptake of CMP NPs. (PDF) |
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July
10 |
Host: James
Ranville, Department of Chemistry and Geochemistry, Colorado School of Mines
Presented by:
Manuel Montaño, Ph.D. Candidate,
Department of Chemistry and Geochemistry, Colorado School of Mines
Topic title:
“Microsecond
spICP-MS for dual-element detection: Environmental and Analytical
Applications”
Abstract:
Single particle ICP-MS
has emerged as a useful analytical technique for the detection and
characterization of engineered nanomaterials (ENMs) in environmental and
analytical matrices. Conventional spICP-MS has used millisecond dwell times,
resulting in the capture of the transient nanoparticle (~500μs) whose
intensity can then be converted into a mass and subsequently a size. Recent
developments have allowed for the implementation of microsecond dwell times,
which significantly improve the ability of spICP-MS to analyze samples at
higher particle number concentrations and amidst higher dissolved analyte
backgrounds. In addition, microsecond dwell times, faster than that of the
nanoparticle event, can open the door for detecting more than one mass in a
single particle. This capability allows for the analysis of complex
nanomaterials, such as those with a core shell structure. It also may be
used to differentiate naturally occurring and engineered nanomaterials by
monitoring differences in the elemental ratios between the two particle
types. The further development of this technique can continue to improve
upon our ability to characterize increasingly complex ENMs and selectively
identify engineered nanomaterials in environmental matrices. (PDF) |
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Aug.
14 |
Host: Reyes
Sierra, Department of Chemical and Environmental Engineering, University of Arizona
Presented by:
Reyes Sierra, Chemical and
Environmental Engineering, University of Arizona
Topic title:
"Fate of CMP Nanoparticles during
Simulated Municipal Wastewater Treatment”
Abstract:
Inorganic oxide NPs
(SiO2, Al2O3, CeO2) are
important components of chemo-mechanical planarization (CMP) slurries used
in the semi-conductor manufacturing. This presentation will describe and
discuss the results of laboratory-scale studies performed to investigate the
fate of CMP nanoparticles during simulated secondary wastewater treatment
(activated sludge process). The results obtained provide new insights that
can facilitate assessment of environmental emissions of CMP nanoparticles.
(PDF) |
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Sept. 18 |
Host: Duane Boning,
Electrical Engineering and Computer Science, Massachusetts Institute of Technology
Presented by:
Dr. Fei Guo, Chemical
Engineering, Massachusetts Institute of Technology
Topic title:
"Development
of Novel Electrospun Fiber Membranes for Membrane Desalination"
Abstract:
Electrospinning is a promising technique for producing nonwoven fiber
membranes having high porosity, small pore size and high surface-to-volume
ratio. Also, the possibility of large scale production combined with the
simplicity of the process makes this technique very attractive for many
different applications. Membrane distillation (MD) is one of the important
application areas for electrospun membranes. MD process is an
environmentally friendly water treatment technique which can be used to
remove ions from various water samples, such as sea water, waste water,
juice, etc. In the MD application, the membrane properties are critical to
the MD performance in terms of permeate flux and salt rejection. The effects
of membrane morphologies, fiber diameter, and membrane hydrophobicity, on
the membrane distillation performance are studied in this work. (PDF) |
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Oct. 2 |
Host: Paul Westerhoff, School
of Sustainable Engineering and The Built Environment, Civil, Environmental
and Sustainable Engineering, Arizona State University
Presented by: Dr. Yu Yang, Postdoctoral Research
Associate, Civil, Environmental and Sustainable Engineering, Arizona State
University
Topic title: "Interaction
of carbon nanotubes and graphene nanoplatelets with wastewater biomass"
Abstract: Municipal sewage and wastewater treatment
plants (WWTPs) have been identified as primary vectors for conveying
nanomaterials from industrial processing and consumer use of nano-enabled
products. We have previously published on methodologies to study wastewater
biomass interaction with C60-fullerenes and metallic nanoparticles to
represent their removal in WWTPs. Recently we have developed digestion and
analytical methods capable of measuring CNTs, nano graphene (GO), or nano
graphene oxide (NGO) materials in the presence of cellular materials. We
will describe the digestion of these cellular materials, through examples
with biomass and lung tissue. Experimental results using these methods with
wastewater biomass and a wide array of CNTs, GO, NGO will be presented. The
data will be interpreted based upon principles of mechanisms that occur at
the interface of nanoparticles and biomass. [Yu Yang,
Paul Westerhoff, Takayuki Nosaka, Kyle Doudrick, Zhicheng Yu, Pierre
Herckes, Kiril Hristovski] (PDF) |
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Nov. 6 |
Host: Ara Philipossian,
Chemical and Environmental Engineering, University of Arizona
Presentation by: Changhong Wu, PhD candidate, and Ara
Philipossian (dissertation adviser), Chemical and Environmental Engineering,
University of Arizona
Topic title: "Pad Surface Thermal Management during Copper
Chemical Mechanical Planarization"
Abstract:
A pad
surface thermal management system is developed to improve copper removal
rate within wafer non-uniformity by locally adjusting the pad surface
temperature. The system consists of one or more thermal transfer modules,
which contact the pad surface during polishing. Hot or cold water circulates
between the thermal transfer module and an external heater or cooler. As the
module is placed on the pad surface, heat conduction occurs between the
module and the pad surface, producing a localized surface with higher or
lower temperatures. It is therefore expected that the local removal rates
will change accordingly since copper chemical mechanical planarization (CMP)
is highly sensitive to temperature. In this study, the system is used to
adjust the “center-fast” removal rate profile to illustrate its effect
during copper CMP. Results show that, when two thermal transfer modules are
employed, local removal rates on the wafer center region decrease
significantly while maintaining the removal rates on the wafer edge region
thus resulting in improved within wafer non-uniformity. (PDF) |
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Dec. 4 |
Host: Srini
Raghavan, University of Arizona => CANCELLED |
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Jan. 8, 2015 |
Host: Farhang
Shadman, Univeristy of Arizona |
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